diff --git a/applications/pass-extension/manifest-chrome.json b/applications/pass-extension/manifest-chrome.json
index f79bda556ff..97673958046 100644
--- a/applications/pass-extension/manifest-chrome.json
+++ b/applications/pass-extension/manifest-chrome.json
@@ -77,6 +77,12 @@
                 "default": "Ctrl+Shift+L"
             },
             "description": "Open Proton Pass in a larger window"
+        },
+        "autofill": {
+            "suggested_key": {
+                "default": "Ctrl+Shift+U"
+            },
+            "description": "Autofill login credentials"
         }
     },
     "icons": {
diff --git a/applications/pass-extension/manifest-firefox.json b/applications/pass-extension/manifest-firefox.json
index f7a66ac42c3..3b23d2e3761 100644
--- a/applications/pass-extension/manifest-firefox.json
+++ b/applications/pass-extension/manifest-firefox.json
@@ -76,6 +76,12 @@
                 "default": "Ctrl+Shift+L"
             },
             "description": "Open Proton Pass in a larger window"
+        },
+        "autofill": {
+            "suggested_key": {
+                "default": "Ctrl+Shift+U"
+            },
+            "description": "Autofill login credentials"
         }
     },
     "icons": {
diff --git a/applications/pass-extension/src/app/content/services/autofill/autofill.service.ts b/applications/pass-extension/src/app/content/services/autofill/autofill.service.ts
index f7633c7db93..efea1492876 100644
--- a/applications/pass-extension/src/app/content/services/autofill/autofill.service.ts
+++ b/applications/pass-extension/src/app/content/services/autofill/autofill.service.ts
@@ -21,6 +21,7 @@ import { first } from '@proton/pass/utils/array/first';
 import { truthy } from '@proton/pass/utils/fp/predicates';
 import { asyncLock } from '@proton/pass/utils/fp/promises';
 import { safeCall } from '@proton/pass/utils/fp/safe-call';
+import { waitUntil } from '@proton/pass/utils/fp/wait-until';
 import { serialize } from '@proton/pass/utils/object/serialize';
 import { uniqueId } from '@proton/pass/utils/string/unique-id';
 import { getEpoch } from '@proton/pass/utils/time/epoch';
@@ -77,6 +78,10 @@ const autofillCounter = (key: keyof AutofillCounters, state: AutofillCounters) =
  * preventing race conditions where focus-to-next-field logic interferes with autofill. */
 const AUTOFILL_LOCK_TIME = BUILD_TARGET === 'safari' ? 250 : 50;
 
+/** Maximum time to wait for the dropdown to become visible before moving keyboard
+ * focus into it when triggered via the autofill shortcut. */
+const DROPDOWN_AUTOFOCUS_TIMEOUT = 1_000;
+
 export const createAutofillService = ({ controller }: ContentScriptContextFactoryOptions) => {
     const state: AutofillState = { processing: false };
 
@@ -372,7 +377,33 @@ export const createAutofillService = ({ controller }: ContentScriptContextFactor
         }
     );
 
+    const onAutofillTrigger: FrameMessageHandler<WorkerMessageType.AUTOFILL_TRIGGER> = withContext(async (ctx) => {
+        const dropdown = ctx?.service.inline.dropdown;
+        const fields = ctx?.service.formManager.getFields();
+        const loginField = fields?.find((field) => field.action?.type === DropdownAction.AUTOFILL_LOGIN);
+
+        if (!dropdown || !loginField) return;
+
+        dropdown.toggle({
+            type: 'field',
+            action: DropdownAction.AUTOFILL_LOGIN,
+            autofocused: false,
+            autofilled: loginField.autofilled !== null,
+            field: loginField,
+        });
+
+        /** Keyboard-only flow: once the dropdown is visible, move keyboard focus into it
+         * so the user can navigate the login suggestions with the arrow keys and select
+         * one with Enter — without touching the mouse. Unlike the focus-on-field flow,
+         * the shortcut opens the dropdown with `autofocused: false`, so nothing has moved
+         * focus into the iframe yet. */
+        await waitUntil(() => dropdown.getState().then(({ visible }) => visible), 25, DROPDOWN_AUTOFOCUS_TIMEOUT)
+            .then(() => dropdown.requestFocus())
+            .catch(noop);
+    });
+
     controller.channel.register(WorkerMessageType.AUTOFILL_SEQUENCE, onAutofillRequest);
+    controller.channel.register(WorkerMessageType.AUTOFILL_TRIGGER, onAutofillTrigger);
 
     return {
         get processing() {
@@ -391,6 +422,7 @@ export const createAutofillService = ({ controller }: ContentScriptContextFactor
         sync,
         destroy: () => {
             controller.channel.unregister(WorkerMessageType.AUTOFILL_SEQUENCE, onAutofillRequest);
+            controller.channel.unregister(WorkerMessageType.AUTOFILL_TRIGGER, onAutofillTrigger);
         },
     };
 };
diff --git a/applications/pass-extension/src/app/content/services/inline/dropdown/app/views/AutofillLogin.tsx b/applications/pass-extension/src/app/content/services/inline/dropdown/app/views/AutofillLogin.tsx
index 206f8cbe540..1d7eaaff50d 100644
--- a/applications/pass-extension/src/app/content/services/inline/dropdown/app/views/AutofillLogin.tsx
+++ b/applications/pass-extension/src/app/content/services/inline/dropdown/app/views/AutofillLogin.tsx
@@ -1,4 +1,4 @@
-import { type FC, useCallback, useEffect, useMemo } from 'react';
+import { type FC, useCallback, useEffect, useMemo, useRef } from 'react';
 
 import type { DropdownAction } from 'proton-pass-extension/app/content/constants.runtime';
 import { DropdownHeader } from 'proton-pass-extension/app/content/services/inline/dropdown/app/components/DropdownHeader';
@@ -19,6 +19,9 @@ import { c } from 'ttag';
 
 import { CircleLoader } from '@proton/atoms/CircleLoader/CircleLoader';
 import Marks from '@proton/components/components/text/Marks';
+import useDropdownArrowNavigation from '@proton/components/hooks/useDropdownArrowNavigation';
+import type { HotkeyTuple } from '@proton/components/hooks/useHotkeys';
+import { useHotkeys } from '@proton/components/hooks/useHotkeys';
 import { usePassCore } from '@proton/pass/components/Core/PassCoreProvider';
 import { UpsellRef } from '@proton/pass/constants';
 import { useMountedState } from '@proton/pass/hooks/useEnsureMounted';
@@ -148,6 +151,26 @@ export const AutofillLogin: FC<Props> = ({ startsWith, action, ...payload }) =>
         [state, filter]
     );
 
+    /** Keyboard navigation over the suggestions. When the dropdown is opened via the autofill
+     * shortcut, focus is moved into the iframe, so the listener is bound to the iframe `document`
+     * (focus lands on the body, outside `rootRef`). Arrow keys move focus across the rows inside
+     * `rootRef` (the header is excluded; the upgrade and empty-state rows stay reachable); Enter
+     * activates the focused item natively (each is a `<button>`); Escape dismisses the dropdown. */
+    const rootRef = useRef<HTMLDivElement>(null);
+    const documentRef = useRef<Document>(document);
+    const { shortcutHandlers } = useDropdownArrowNavigation({ rootRef });
+    const hotkeys: HotkeyTuple[] = [
+        ...shortcutHandlers,
+        [
+            'Escape',
+            (e) => {
+                e.preventDefault();
+                controller.close({ userAction: true });
+            },
+        ],
+    ];
+    useHotkeys(documentRef, hotkeys);
+
     if (loading) return <CircleLoader className="absolute inset-center m-auto" />;
 
     return (
@@ -163,16 +186,18 @@ export const AutofillLogin: FC<Props> = ({ startsWith, action, ...payload }) =>
                     />
                 }
             />
-            {dropdownItems.length > 0 ? (
-                <ScrollableItemsList>{dropdownItems}</ScrollableItemsList>
-            ) : (
-                <ListItem
-                    icon={{ type: 'status', icon: PassIconStatus.ACTIVE }}
-                    onClick={controller.close}
-                    title={PASS_APP_NAME}
-                    subTitle={c('Info').t`No login found`}
-                />
-            )}
+            <div ref={rootRef}>
+                {dropdownItems.length > 0 ? (
+                    <ScrollableItemsList>{dropdownItems}</ScrollableItemsList>
+                ) : (
+                    <ListItem
+                        icon={{ type: 'status', icon: PassIconStatus.ACTIVE }}
+                        onClick={controller.close}
+                        title={PASS_APP_NAME}
+                        subTitle={c('Info').t`No login found`}
+                    />
+                )}
+            </div>
         </>
     );
 };
diff --git a/applications/pass-extension/src/app/content/services/inline/dropdown/dropdown.abstract.ts b/applications/pass-extension/src/app/content/services/inline/dropdown/dropdown.abstract.ts
index 9bd11857e2c..b45d6d5f7a5 100644
--- a/applications/pass-extension/src/app/content/services/inline/dropdown/dropdown.abstract.ts
+++ b/applications/pass-extension/src/app/content/services/inline/dropdown/dropdown.abstract.ts
@@ -15,6 +15,7 @@ export interface DropdownHandler {
     close: (target?: InlineFieldTarget | InlineFrameTarget) => void;
     destroy: () => void;
     toggle: (request: DropdownRequest) => void;
+    requestFocus: () => Promise<void>;
     sendMessage: (message: InlineMessage) => void;
     getState: (checkInFlight?: boolean) => Promise<DropdownStateDTO>;
 }
diff --git a/applications/pass-extension/src/app/content/services/inline/dropdown/dropdown.app.ts b/applications/pass-extension/src/app/content/services/inline/dropdown/dropdown.app.ts
index 180f1dd2ee5..570c1b50f5c 100644
--- a/applications/pass-extension/src/app/content/services/inline/dropdown/dropdown.app.ts
+++ b/applications/pass-extension/src/app/content/services/inline/dropdown/dropdown.app.ts
@@ -48,6 +48,7 @@ export interface DropdownApp extends InlineAppHandler<DropdownRequest> {
      * UX decisions with regards to dropdown interaction */
     anchor: MaybeNull<DropdownAnchor>;
     focused: boolean;
+    requestFocus: () => Promise<void>;
 }
 
 export const createDropdown = (popover: PopoverController): DropdownApp => {
@@ -170,6 +171,7 @@ export const createDropdown = (popover: PopoverController): DropdownApp => {
             return focus.focused || focus.willFocus;
         },
 
+        requestFocus: focus.requestFocus,
         close: iframe.close,
         destroy: iframe.destroy,
         getState: () => iframe.state,
diff --git a/applications/pass-extension/src/app/content/services/inline/dropdown/dropdown.focus.ts b/applications/pass-extension/src/app/content/services/inline/dropdown/dropdown.focus.ts
index e08ba8df7a6..17befdda5f4 100644
--- a/applications/pass-extension/src/app/content/services/inline/dropdown/dropdown.focus.ts
+++ b/applications/pass-extension/src/app/content/services/inline/dropdown/dropdown.focus.ts
@@ -29,6 +29,7 @@ export const DROPDOWN_FOCUS_TRAP_TIMEOUT = 500;
 export interface DropdownFocusController {
     focused: boolean;
     willFocus: boolean;
+    requestFocus: () => Promise<void>;
     disconnect: () => void;
 }
 
@@ -92,7 +93,12 @@ export const createDropdownFocusController = ({
     };
 
     const onWillFocus = () => {
-        if (anchor.current?.type === 'field') anchor.current.field.preventAction();
+        /** Only arm the field action-trap when the anchor field is the active element — i.e. the
+         * focus-recovery scenario. The shortcut flow opens the dropdown without focusing the field,
+         * so arming it there would needlessly suppress the field's normal autofocus dropdown. */
+        if (anchor.current?.type === 'field' && isActiveElement(anchor.current.field.element)) {
+            anchor.current.field.preventAction();
+        }
         clearTimeout(state.willFocusTimer);
         state.willFocus = true;
         state.willFocusTimer = setTimeout(disconnect, DROPDOWN_FOCUS_TRAP_TIMEOUT);
@@ -165,6 +171,7 @@ export const createDropdownFocusController = ({
         get willFocus() {
             return state.willFocus;
         },
+        requestFocus: onFocusRequest,
         disconnect,
     };
 };
diff --git a/applications/pass-extension/src/app/content/services/inline/dropdown/dropdown.handler.ts b/applications/pass-extension/src/app/content/services/inline/dropdown/dropdown.handler.ts
index eb74dead9b2..16f714ce6d3 100644
--- a/applications/pass-extension/src/app/content/services/inline/dropdown/dropdown.handler.ts
+++ b/applications/pass-extension/src/app/content/services/inline/dropdown/dropdown.handler.ts
@@ -134,6 +134,8 @@ export const createDropdownHandler = (registry: InlineRegistry): DropdownHandler
             registry.dropdown?.destroy();
         },
 
+        requestFocus: () => registry.dropdown?.requestFocus() ?? Promise.resolve(),
+
         sendMessage: (message) => registry.dropdown?.sendMessage(message),
 
         getState: async (checkInFlight) => {
diff --git a/applications/pass-extension/src/lib/components/Inline/ListItem.scss b/applications/pass-extension/src/lib/components/Inline/ListItem.scss
index 46209c960d9..9632321640b 100644
--- a/applications/pass-extension/src/lib/components/Inline/ListItem.scss
+++ b/applications/pass-extension/src/lib/components/Inline/ListItem.scss
@@ -3,4 +3,13 @@ button.pass-injected-dropdown--item {
 		cursor: default;
 		background-color: transparent;
 	}
+
+	// Keyboard navigation: highlight the focused suggestion like hover so the active item is
+	// obvious when navigating the list with the arrow keys. `:focus` (not only `:focus-visible`)
+	// because navigation focuses items programmatically, which some engines do not treat as
+	// focus-visible.
+	&:focus,
+	&:focus-visible {
+		background-color: var(--interaction-default-hover);
+	}
 }
diff --git a/applications/pass-extension/src/lib/extension/commands.spec.ts b/applications/pass-extension/src/lib/extension/commands.spec.ts
new file mode 100644
index 00000000000..8e07aa533ab
--- /dev/null
+++ b/applications/pass-extension/src/lib/extension/commands.spec.ts
@@ -0,0 +1,58 @@
+import { handleExtensionCommand } from './commands';
+import browser from '@proton/pass/lib/globals/browser';
+import { WorkerMessageType } from 'proton-pass-extension/types/messages';
+
+jest.mock('@proton/pass/lib/globals/browser', () => ({
+    tabs: {
+        create: jest.fn(() => Promise.resolve()),
+        query: jest.fn(() => Promise.resolve([{ id: 42 }])),
+        sendMessage: jest.fn(() => Promise.resolve()),
+    },
+    runtime: {
+        getURL: jest.fn((path: string) => `chrome-extension://abc/${path}`),
+    },
+    commands: {
+        getAll: jest.fn(() => Promise.resolve([])),
+    },
+}));
+
+describe('handleExtensionCommand', () => {
+    beforeEach(() => jest.clearAllMocks());
+
+    it('should open larger window for open-larger-window command', async () => {
+        await handleExtensionCommand('open-larger-window');
+        expect(browser.tabs.create).toHaveBeenCalledWith({
+            url: 'chrome-extension://abc/popup.html#',
+        });
+    });
+
+    it('should send AUTOFILL_TRIGGER to active tab for autofill command', async () => {
+        await handleExtensionCommand('autofill');
+        expect(browser.tabs.query).toHaveBeenCalledWith({ active: true, currentWindow: true });
+        expect(browser.tabs.sendMessage).toHaveBeenCalledWith(
+            42,
+            expect.objectContaining({ type: WorkerMessageType.AUTOFILL_TRIGGER })
+        );
+    });
+
+    it('should send message when tab id is 0', async () => {
+        (browser.tabs.query as jest.Mock).mockResolvedValueOnce([{ id: 0 }]);
+        await handleExtensionCommand('autofill');
+        expect(browser.tabs.sendMessage).toHaveBeenCalledWith(
+            0,
+            expect.objectContaining({ type: WorkerMessageType.AUTOFILL_TRIGGER })
+        );
+    });
+
+    it('should not send message when no active tab', async () => {
+        (browser.tabs.query as jest.Mock).mockResolvedValueOnce([]);
+        await handleExtensionCommand('autofill');
+        expect(browser.tabs.sendMessage).not.toHaveBeenCalled();
+    });
+
+    it('should do nothing for unknown commands', async () => {
+        await handleExtensionCommand('unknown-command');
+        expect(browser.tabs.create).not.toHaveBeenCalled();
+        expect(browser.tabs.sendMessage).not.toHaveBeenCalled();
+    });
+});
diff --git a/applications/pass-extension/src/lib/extension/commands.ts b/applications/pass-extension/src/lib/extension/commands.ts
index fce78a34622..068963638f1 100644
--- a/applications/pass-extension/src/lib/extension/commands.ts
+++ b/applications/pass-extension/src/lib/extension/commands.ts
@@ -1,6 +1,9 @@
 import browser from '@proton/pass/lib/globals/browser';
 import noop from '@proton/utils/noop';
 
+import { backgroundMessage } from 'proton-pass-extension/lib/message/send-message';
+import { WorkerMessageType } from 'proton-pass-extension/types/messages';
+
 export type Shortcut = { name: string; description: string; shortcut: string };
 
 type BrowserCommand = Awaited<ReturnType<typeof browser.commands.getAll>>[number];
@@ -10,7 +13,7 @@ export const resolveShortcuts = (commands: BrowserCommand[], supported: Record<s
         .filter((cmd): cmd is BrowserCommand & { name: string } => Boolean(cmd.name && cmd.name in supported))
         .map(({ name, shortcut }) => ({ name, shortcut: shortcut ?? '', description: supported[name] }));
 
-export const handleExtensionCommand = (command: string) => {
+export const handleExtensionCommand = async (command: string) => {
     if (command === 'open-larger-window') {
         browser.tabs
             .create({
@@ -18,4 +21,11 @@ export const handleExtensionCommand = (command: string) => {
             })
             .catch(noop);
     }
+
+    if (command === 'autofill') {
+        const [tab] = await browser.tabs.query({ active: true, currentWindow: true });
+        if (tab?.id != null) {
+            browser.tabs.sendMessage(tab.id, backgroundMessage({ type: WorkerMessageType.AUTOFILL_TRIGGER })).catch(noop);
+        }
+    }
 };
diff --git a/applications/pass-extension/src/types/messages.ts b/applications/pass-extension/src/types/messages.ts
index 00d13211425..4f1875fdb91 100644
--- a/applications/pass-extension/src/types/messages.ts
+++ b/applications/pass-extension/src/types/messages.ts
@@ -104,6 +104,7 @@ export enum WorkerMessageType {
     AUTOFILL_OTP_CHECK = 'AUTOFILL_OTP_CHECK',
     AUTOFILL_SEQUENCE = 'AUTOFILL_SEQUENCE',
     AUTOFILL_SYNC = 'AUTOFILL_SYNC',
+    AUTOFILL_TRIGGER = 'AUTOFILL_TRIGGER',
 
     AUTOSAVE_REQUEST = 'AUTOSAVE_REQUEST',
     AUTOSUGGEST_ALIAS = 'AUTOSUGGEST_ALIAS',
@@ -212,6 +213,7 @@ export type AutofillOTPCheckMessage = { type: WorkerMessageType.AUTOFILL_OTP_CHE
 export type AutofillPasswordOptionsMessage = { type: WorkerMessageType.AUTOSUGGEST_PASSWORD };
 export type AutofillSequenceMessage = WithPayload<WorkerMessageType.AUTOFILL_SEQUENCE, AutofillRequest>;
 export type AutofillSyncMessage = { type: WorkerMessageType.AUTOFILL_SYNC };
+export type AutofillTriggerMessage = { type: WorkerMessageType.AUTOFILL_TRIGGER };
 
 export type AutoSaveRequestMessage = WithPayload<WorkerMessageType.AUTOSAVE_REQUEST, AutosaveRequest>;
 export type AutosuggestAliasMessage = { type: WorkerMessageType.AUTOSUGGEST_ALIAS };
@@ -315,6 +317,7 @@ export type WorkerMessage =
     | AutofillPasswordOptionsMessage
     | AutofillSequenceMessage
     | AutofillSyncMessage
+    | AutofillTriggerMessage
     | AutoSaveRequestMessage
     | AutosuggestAliasMessage
     | B2BEventMessage