diff --git a/.github/workflows/pre-commit.yml b/.github/workflows/pre-commit.yml
index 011ccebadc..9b14c208e5 100644
--- a/.github/workflows/pre-commit.yml
+++ b/.github/workflows/pre-commit.yml
@@ -18,7 +18,7 @@ jobs:
       - name: Setup Python
         uses: actions/setup-python@v4
         with:
-          python-version: '3.10'
+          python-version: '3.12'
 
       - name: Run Lint
         uses: pre-commit/action@v3.0.0
diff --git a/.github/workflows/quicktest-dev-pr.yml b/.github/workflows/quicktest-dev-pr.yml
index c439041c85..32b95c82a0 100644
--- a/.github/workflows/quicktest-dev-pr.yml
+++ b/.github/workflows/quicktest-dev-pr.yml
@@ -11,7 +11,7 @@ jobs:
 
   test:
     name: Run quicktest on PR branch
-    runs-on: ubuntu-22.04
+    runs-on: ubuntu-24.04
 
     steps:
       - name: checkout
diff --git a/.github/workflows/quicktest-local.yml b/.github/workflows/quicktest-local.yml
index e8e1a845ae..83c43b8eec 100644
--- a/.github/workflows/quicktest-local.yml
+++ b/.github/workflows/quicktest-local.yml
@@ -13,7 +13,7 @@ jobs:
 
   test:
     name: Run quicktest with local installation (no Docker)
-    runs-on: ubuntu-22.04
+    runs-on: ubuntu-24.04
 
     steps:
       - name: Checkout
diff --git a/.pre-commit-config.yaml b/.pre-commit-config.yaml
index 98966bb865..8b710595b1 100644
--- a/.pre-commit-config.yaml
+++ b/.pre-commit-config.yaml
@@ -29,7 +29,7 @@
 exclude: '^docs/conf.py'
 
 default_language_version:
-    python: python3.10
+    python: python3.12
 
 repos:
 - repo: https://github.com/pre-commit/pre-commit-hooks
diff --git a/.readthedocs.yaml b/.readthedocs.yaml
index 591a14b413..7e7b7c08f4 100644
--- a/.readthedocs.yaml
+++ b/.readthedocs.yaml
@@ -34,9 +34,9 @@ version: 2
 
 # Set the version of Python and other tools you might need
 build:
-  os: ubuntu-22.04
+  os: ubuntu-24.04
   tools:
-    python: "3.10"
+    python: "3.12"
 
 sphinx:
    configuration: docs/finn/conf.py
diff --git a/docker/Dockerfile.finn b/docker/Dockerfile.finn
index 4614019134..35331c0b2a 100644
--- a/docker/Dockerfile.finn
+++ b/docker/Dockerfile.finn
@@ -27,7 +27,7 @@
 # OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
 # OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
 
-FROM ubuntu:jammy-20230126
+FROM ubuntu:noble-20240605
 LABEL maintainer="Jakoba Petri-Koenig <jakoba.petri-koenig@amd.com>, Yaman Umuroglu <yaman.umuroglu@amd.com>"
 
 ARG XRT_DEB_VERSION="xrt_202220.2.14.354_22.04-amd64-xrt"
@@ -66,7 +66,7 @@ RUN apt-get update && \
     unzip \
     zip \
     locales \
-    lsb-core \
+    lsb-release \
     python3 \
     python-is-python3 \
     python3-pip \
@@ -77,8 +77,8 @@ RUN apt-get update && \
     libboost-dev \
     libjansson-dev \
     libgetdata-dev \
-    libtinfo5 \
-    g++-10 \
+    libncurses6 \
+    g++ \
     cmake
 RUN echo "StrictHostKeyChecking no" >> /etc/ssh/ssh_config
 RUN locale-gen "en_US.UTF-8"
@@ -101,51 +101,52 @@ RUN if [ -z "$SKIP_XRT" ];then \
 
 # versioned Python package requirements for FINN compiler
 # these are given in requirements.txt
-RUN pip install -r /tmp/requirements.txt
+RUN pip install --break-system-packages -r /tmp/requirements.txt
 RUN rm /tmp/requirements.txt
 
 # install PyTorch
-RUN pip install torch==2.8.0 torchvision==0.23.0 torchaudio==2.8.0 --extra-index-url https://download.pytorch.org/whl/cu126
+RUN pip install --break-system-packages torch==2.8.0 torchvision==0.23.0 torchaudio==2.8.0 --extra-index-url https://download.pytorch.org/whl/cu126
 
 # extra Python package dependencies (for testing and interaction)
-RUN pip install pygments==2.14.0
-RUN pip install ipykernel==6.21.2
-RUN pip install jupyter==1.0.0 --ignore-installed
+RUN pip install --break-system-packages pygments==2.17.2
+RUN pip install --break-system-packages --ignore-installed typing_extensions
+RUN pip install --break-system-packages ipykernel==6.29.0
+RUN pip install --break-system-packages jupyter==1.0.0
 # anyio >= 4.13.0 for jupyter incompatible with pytest 6.2.5 (missing _pytest.scope module, added in pytest 7.0.0)
-RUN pip install 'anyio<4.13'
-RUN pip install markupsafe==2.0.1
-RUN pip install matplotlib==3.7.0  --ignore-installed
-RUN pip install pytest-dependency==0.5.1
-RUN pip install pytest-xdist[setproctitle]==3.2.0
-RUN pip install pytest-parallel==0.1.1
+RUN pip install --break-system-packages 'anyio<4.13'
+RUN pip install --break-system-packages markupsafe==2.1.5
+RUN pip install --break-system-packages matplotlib==3.8.2
+RUN pip install --break-system-packages pytest-dependency==0.5.1
+RUN pip install --break-system-packages pytest-xdist[setproctitle]==3.2.0
+RUN pip install --break-system-packages pytest-parallel==0.1.1
 # Beyond version 8.5.0, subsequent Netron calls in a Jupyter notebook cause "Address already in use" errors
-RUN pip install netron
-RUN pip install pandas==1.5.3
-RUN pip install scikit-learn==1.2.1
-RUN pip install tqdm==4.64.1
-RUN pip install -e git+https://github.com/fbcotter/dataset_loading.git@0.0.4#egg=dataset_loading
+RUN pip install --break-system-packages netron
+RUN pip install --break-system-packages pandas==2.1.4
+RUN pip install --break-system-packages scikit-learn==1.4.0
+RUN pip install --break-system-packages tqdm==4.64.1
+RUN pip install --break-system-packages git+https://github.com/fbcotter/dataset_loading.git@0.0.4#egg=dataset_loading
 # these versions of pytest and associated plugins allow for stable collection of
 # test reports and code coverage reports in HTML
-RUN pip install pytest==6.2.5
-RUN pip install pytest-metadata==1.7.0
-RUN pip install pytest-html==3.0.0
-RUN pip install pytest-html-merger==0.0.8
-RUN pip install pytest-cov==4.1.0
-RUN pip install pyyaml==6.0.1
+RUN pip install --break-system-packages pytest==7.4.4
+RUN pip install --break-system-packages pytest-metadata==1.7.0
+RUN pip install --break-system-packages pytest-html==3.0.0
+RUN pip install --break-system-packages pytest-html-merger==0.0.8
+RUN pip install --break-system-packages pytest-cov==4.1.0
+RUN pip install --break-system-packages pyyaml==6.0.1
 
 # extra dependencies from other FINN deps
 # installed in Docker image to make entrypoint script go faster
 # finn-experimental
-RUN pip install deap==1.3.1
-RUN pip install mip==1.13.0
-RUN pip install networkx==2.8
+RUN pip install --break-system-packages deap==1.4.1
+RUN pip install --break-system-packages mip==1.13.0
+RUN pip install --break-system-packages networkx==2.8
 # brevitas
-RUN pip install future-annotations==1.0.0
-RUN pip install dependencies==2.0.1
-RUN pip install tokenize-rt==4.2.1
+RUN pip install --break-system-packages future-annotations==1.0.0
+RUN pip install --break-system-packages dependencies==2.0.1
+RUN pip install --break-system-packages tokenize-rt==4.2.1
 
 # assure that we have the right setuptools version
-RUN pip install setuptools==68.2.2
+RUN pip install --break-system-packages setuptools==68.2.2
 
 # extra environment variables for FINN compiler
 ENV VIVADO_IP_CACHE "/tmp/vivado_ip_cache"
diff --git a/docker/finn_entrypoint.sh b/docker/finn_entrypoint.sh
index 98016f99cc..7b4a08c46e 100644
--- a/docker/finn_entrypoint.sh
+++ b/docker/finn_entrypoint.sh
@@ -63,18 +63,18 @@ _qonnx_pyproj_toml="${FINN_ROOT}/deps/qonnx/pyproject.toml"
 _qonnx_pyproj_tmp="${FINN_ROOT}/deps/qonnx/pyproject.tmp"
 mv "$_qonnx_pyproj_toml" "$_qonnx_pyproj_tmp"
 trap 'mv "$_qonnx_pyproj_tmp" "$_qonnx_pyproj_toml" 2>/dev/null || true' EXIT
-pip install --user -e "${FINN_ROOT}/deps/qonnx"
+pip install --break-system-packages --user -e "${FINN_ROOT}/deps/qonnx"
 mv "$_qonnx_pyproj_tmp" "$_qonnx_pyproj_toml"
 trap - EXIT
 
 # finn-experimental
-pip install --user -e "${FINN_ROOT}/deps/finn-experimental"
+pip install --break-system-packages --user -e "${FINN_ROOT}/deps/finn-experimental"
 # brevitas
-pip install --user -e "${FINN_ROOT}/deps/brevitas"
+pip install --break-system-packages --user -e "${FINN_ROOT}/deps/brevitas"
 
 if [ -f "${FINN_ROOT}/setup.py" ];then
   # run pip install for finn
-  pip install --user -e "${FINN_ROOT}"
+  pip install --break-system-packages --user -e "${FINN_ROOT}"
 else
   recho "Unable to find FINN source code in ${FINN_ROOT}"
   recho "Ensure you have passed -v <path-to-finn-repo>:<path-to-finn-repo> to the docker run command"
@@ -93,8 +93,7 @@ if [ -f "$VITIS_PATH/settings64.sh" ];then
     source "$XILINX_XRT/setup.sh" || true
     gecho "Found XRT at $XILINX_XRT"
   else
-    recho "XRT not found on $XILINX_XRT, did you skip the download or did the installation fail?"
-    exit -1
+    yecho "XRT not found on $XILINX_XRT, Alveo U-series devices (U250, U280, U50, U55C, etc.) functionality will not be available."
   fi
 else
   yecho "Unable to find $VITIS_PATH/settings64.sh"
diff --git a/requirements.txt b/requirements.txt
index 19007b68ac..26d456e487 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -3,19 +3,19 @@ clize==5.0.1
 dataclasses-json==0.5.7
 gspread==3.6.0
 importlib-resources==6.1.0
-ipython==8.12.2
-numpy==1.24.1
-onnx==1.17.0
+ipython==8.18.1
+numpy==1.26.4
+onnx==1.21.0
 onnxoptimizer
-onnxruntime==1.18.1
+onnxruntime==1.26.0
 onnxscript==0.6.2
-pre-commit==3.3.2
+pre-commit==3.5.0
 protobuf==5.29.6
 psutil==5.9.4
-pybind11==2.10.0
-pyscaffold==4.6
+pybind11==2.11.1
+pyscaffold==4.5
 pytest-forked==1.6.0
-scipy==1.10.1
+scipy==1.11.4
 setupext-janitor>=1.1.2
 sigtools==4.0.1
 toposort==1.7.0
diff --git a/run-docker.sh b/run-docker.sh
index dcda41f428..bba1189fac 100755
--- a/run-docker.sh
+++ b/run-docker.sh
@@ -57,8 +57,8 @@ if [ -z "$PLATFORM_REPO_PATHS" ];then
 fi
 
 if [ -z "$V80PP_DEB_PACKAGE" ];then
-  recho "Please set V80PP_DEB_PACKAGE pointing to the SLASH v80++ .deb package."
-  recho "This is required to be able to use the Alveo V80 card."
+  yecho "Please set V80PP_DEB_PACKAGE pointing to the SLASH v80++ .deb package."
+  yecho "This is required to be able to use the Alveo V80 card."
 fi
 
 DOCKER_GID=$(id -g)
diff --git a/setup-local.sh b/setup-local.sh
index a9b25f5f4a..ddaa87944b 100755
--- a/setup-local.sh
+++ b/setup-local.sh
@@ -100,14 +100,14 @@ echo ""
 # Step 1: Check prerequisites
 gecho "Step 1: Checking prerequisites..."
 
-# Check Python version (require 3.10+)
+# Check Python version (require 3.12+)
 PYTHON_VERSION=$(python3 --version 2>&1 | cut -d' ' -f2)
 PYTHON_MAJOR=$(echo $PYTHON_VERSION | cut -d'.' -f1)
 PYTHON_MINOR=$(echo $PYTHON_VERSION | cut -d'.' -f2)
 
-if [[ $PYTHON_MAJOR -lt 3 ]] || [[ $PYTHON_MAJOR -eq 3 && $PYTHON_MINOR -lt 10 ]]; then
-    recho "Python 3.10 or higher required, found $PYTHON_VERSION"
-    recho "Set FINN_PYTHON to point to a Python 3.10+ interpreter"
+if [[ $PYTHON_MAJOR -lt 3 ]] || [[ $PYTHON_MAJOR -eq 3 && $PYTHON_MINOR -lt 12 ]]; then
+    recho "Python 3.12 or higher required, found $PYTHON_VERSION"
+    recho "Set FINN_PYTHON to point to a Python 3.12+ interpreter"
     exit 1
 fi
 gecho "  Python $PYTHON_VERSION - OK"
@@ -158,10 +158,10 @@ if [ -d "$VENV_DIR" ]; then
     yecho "Virtual environment already exists at $VENV_DIR"
     yecho "Reusing existing environment. Delete .venv to start fresh."
 else
-    # Use FINN_PYTHON if set, otherwise look for Python 3.10
+    # Use FINN_PYTHON if set, otherwise look for Python 3.12
     if [ -z "$FINN_PYTHON" ]; then
-        if [ -x "/usr/bin/python3.10" ]; then
-            FINN_PYTHON="/usr/bin/python3.10"
+        if [ -x "/usr/bin/python3.12" ]; then
+            FINN_PYTHON="/usr/bin/python3.12"
         else
             FINN_PYTHON="python3"
         fi
diff --git a/setup.cfg b/setup.cfg
index c9ce06b962..ceb683c40d 100644
--- a/setup.cfg
+++ b/setup.cfg
@@ -59,7 +59,7 @@ package_dir =
 # The usage of test_requires is discouraged, see `Dependency Management` docs
 # tests_require = pytest; pytest-cov
 # Require a specific Python version, e.g. Python 2.7 or >= 3.4
-# python_requires = >=2.7,!=3.0.*,!=3.1.*,!=3.2.*,!=3.3.*
+python_requires = >=3.12
 
 [options.packages.find]
 where = src
diff --git a/src/finn/transformation/general.py b/src/finn/transformation/general.py
index b245ee4c90..5c5f3eafdc 100644
--- a/src/finn/transformation/general.py
+++ b/src/finn/transformation/general.py
@@ -16,7 +16,7 @@
 import warnings
 
 # Protobuf onnx graph node type
-from onnx import AttributeProto, NodeProto, mapping  # noqa
+from onnx import AttributeProto
 from qonnx.custom_op.registry import getCustomOp, is_custom_op
 from qonnx.transformation.base import Transformation