diff --git a/rdagent/app/utils/health_check.py b/rdagent/app/utils/health_check.py
index 95597b257..467d2d23d 100644
--- a/rdagent/app/utils/health_check.py
+++ b/rdagent/app/utils/health_check.py
@@ -3,9 +3,6 @@
 
 import docker
 import fire
-import litellm
-from litellm import completion, embedding
-from litellm.utils import ModelResponse
 
 from rdagent.log import rdagent_logger as logger
 from rdagent.utils.env import cleanup_container
@@ -51,24 +48,11 @@ def check_and_list_free_ports(start_port=19899, max_ports=10) -> None:
 def test_chat(chat_model, chat_api_key, chat_api_base):
     logger.info(f"🧪 Testing chat model: {chat_model}")
     try:
-        if chat_api_base is None:
-            response: ModelResponse = completion(
-                model=chat_model,
-                api_key=chat_api_key,
-                messages=[
-                    {"role": "user", "content": "Hello!"},
-                ],
-            )
-        else:
-            response: ModelResponse = completion(
-                model=chat_model,
-                api_key=chat_api_key,
-                api_base=chat_api_base,
-                messages=[
-                    {"role": "user", "content": "Hello!"},
-                ],
-            )
-        logger.info(f"✅ Chat test passed.")
+        from rdagent.oai.backend.litellm import LiteLLMAPIBackend
+
+        backend = LiteLLMAPIBackend()
+        backend.build_messages_and_create_chat_completion(user_prompt="Hello!")
+        logger.info("✅ Chat test passed.")
         return True
     except Exception as e:
         logger.error(f"❌ Chat test failed: {e}")
@@ -78,12 +62,10 @@ def test_chat(chat_model, chat_api_key, chat_api_base):
 def test_embedding(embedding_model, embedding_api_key, embedding_api_base):
     logger.info(f"🧪 Testing embedding model: {embedding_model}")
     try:
-        response = embedding(
-            model=embedding_model,
-            api_key=embedding_api_key,
-            api_base=embedding_api_base,
-            input="Hello world!",
-        )
+        from rdagent.oai.backend.litellm import LiteLLMAPIBackend
+
+        backend = LiteLLMAPIBackend()
+        backend.create_embedding(input_content="Hello world!")
         logger.info("✅ Embedding test passed.")
         return True
     except Exception as e:
@@ -117,6 +99,13 @@ def env_check():
         embedding_model = os.getenv("EMBEDDING_MODEL")
         embedding_api_key = chat_api_key
         embedding_api_base = chat_api_base
+    elif "CHAT_OPENAI_COMPATIBLE_API_KEY" in os.environ or "EMBEDDING_OPENAI_COMPATIBLE_API_KEY" in os.environ:
+        chat_api_key = os.getenv("CHAT_OPENAI_COMPATIBLE_API_KEY")
+        chat_api_base = os.getenv("CHAT_OPENAI_COMPATIBLE_API_BASE")
+        chat_model = os.getenv("CHAT_MODEL")
+        embedding_model = os.getenv("EMBEDDING_MODEL")
+        embedding_api_key = os.getenv("EMBEDDING_OPENAI_COMPATIBLE_API_KEY")
+        embedding_api_base = os.getenv("EMBEDDING_OPENAI_COMPATIBLE_API_BASE")
     else:
         logger.error("No valid configuration was found, please check your .env file.")
 
diff --git a/rdagent/oai/backend/litellm.py b/rdagent/oai/backend/litellm.py
index 86cbe8461..9dd489000 100644
--- a/rdagent/oai/backend/litellm.py
+++ b/rdagent/oai/backend/litellm.py
@@ -79,10 +79,24 @@ def _create_embedding_inner_function(self, input_content_list: list[str]) -> lis
                 f"{LogColors.MAGENTA}Creating embedding{LogColors.END} for: {input_content_list}",
                 tag="debug_litellm_emb",
             )
-        response = embedding(
-            model=model_name,
-            input=input_content_list,
-        )
+        call_kwargs = {
+            "model": model_name,
+            "input": input_content_list,
+        }
+        if LITELLM_SETTINGS.embedding_extra_params:
+            if isinstance(LITELLM_SETTINGS.embedding_extra_params, dict):
+                call_kwargs.update(LITELLM_SETTINGS.embedding_extra_params)
+            else:
+                logger.error(
+                    f"{LogColors.RED}embedding_extra_params must be a dict, got {type(LITELLM_SETTINGS.embedding_extra_params).__name__}. Ignoring extra params.{LogColors.END}",
+                    tag="debug_litellm_emb",
+                )
+        # Use embedding OpenAI-Compatible config
+        if LITELLM_SETTINGS.embedding_openai_compatible_api_key:
+            call_kwargs["api_key"] = LITELLM_SETTINGS.embedding_openai_compatible_api_key
+        if LITELLM_SETTINGS.embedding_openai_compatible_api_base:
+            call_kwargs["api_base"] = LITELLM_SETTINGS.embedding_openai_compatible_api_base
+        response = embedding(**call_kwargs)
         response_list = [data["embedding"] for data in response.data]
         return response_list
 
@@ -152,6 +166,12 @@ def _create_chat_completion_inner_function(  # type: ignore[no-untyped-def] # no
         complete_kwargs = self.get_complete_kwargs()
         model = complete_kwargs["model"]
 
+        # Use OpenAI-Compatible API config for chat completion
+        if LITELLM_SETTINGS.chat_openai_compatible_api_key:
+            complete_kwargs["api_key"] = LITELLM_SETTINGS.chat_openai_compatible_api_key
+        if LITELLM_SETTINGS.chat_openai_compatible_api_base:
+            complete_kwargs["api_base"] = LITELLM_SETTINGS.chat_openai_compatible_api_base
+
         response = completion(
             messages=messages,
             stream=LITELLM_SETTINGS.chat_stream,
diff --git a/rdagent/oai/llm_conf.py b/rdagent/oai/llm_conf.py
index a9a1130e7..708b494b0 100644
--- a/rdagent/oai/llm_conf.py
+++ b/rdagent/oai/llm_conf.py
@@ -66,6 +66,9 @@ class LLMSettings(ExtendedBaseSettings):
     chat_openai_base_url: str | None = None  #
     chat_azure_api_base: str = ""
     chat_azure_api_version: str = ""
+    # OpenAI-Compatible API config (for chat completion)
+    chat_openai_compatible_api_key: str = ""
+    chat_openai_compatible_api_base: str = ""
     chat_max_tokens: int | None = None
     chat_temperature: float = 0.5
     chat_stream: bool = True
@@ -87,6 +90,10 @@ class LLMSettings(ExtendedBaseSettings):
     embedding_azure_api_version: str = ""
     embedding_max_str_num: int = 50
     embedding_max_length: int = 8192
+    embedding_extra_params: dict = {}
+    # OpenAI-Compatible API config (for embedding)
+    embedding_openai_compatible_api_key: str = ""
+    embedding_openai_compatible_api_base: str = ""
 
     # offline llama2 related config
     use_llama2: bool = False