diff --git a/.gitignore b/.gitignore
index f8cfb6a0..54347507 100644
--- a/.gitignore
+++ b/.gitignore
@@ -323,3 +323,4 @@ src/ontology/reports/xrefs.tsv
 src/ontology/imports/*.json
 /src/metadata
 src/mappings/*.owl
+.claude/
diff --git a/src/patterns/dosdp-dev/abnormalLevelOfChemicalEntity.yaml b/src/patterns/dosdp-dev/abnormalLevelOfChemicalEntity.yaml
index 42abf912..02425335 100644
--- a/src/patterns/dosdp-dev/abnormalLevelOfChemicalEntity.yaml
+++ b/src/patterns/dosdp-dev/abnormalLevelOfChemicalEntity.yaml
@@ -16,11 +16,13 @@ classes:
   amount: PATO:0000070
   abnormal: PATO:0000460
   chemical entity: CHEBI:24431
+  anatomical entity: UBERON:0001062
 
 relations:
   inheres_in: RO:0000052
   has_modifier: RO:0002573
   has_part: BFO:0000051
+  part_of: BFO:0000050
 
 annotationProperties:
   exact_synonym: oio:hasExactSynonym 
@@ -40,7 +42,7 @@ def:
     - chemical_entity
 
 equivalentTo:
-  text: "'has_part' some ('amount' and ('inheres_in' some %s) and ('has_modifier' some 'abnormal'))"
+  text: "'has_part' some ('amount' and ('inheres_in' some (%s and ('part_of' some 'anatomical entity'))) and ('has_modifier' some 'abnormal'))"
   vars:
     - chemical_entity
 
diff --git a/src/patterns/dosdp-dev/abnormalLevelOfChemicalEntityWithRole.yaml b/src/patterns/dosdp-dev/abnormalLevelOfChemicalEntityWithRole.yaml
index 7c048b50..3ffe2905 100644
--- a/src/patterns/dosdp-dev/abnormalLevelOfChemicalEntityWithRole.yaml
+++ b/src/patterns/dosdp-dev/abnormalLevelOfChemicalEntityWithRole.yaml
@@ -11,12 +11,14 @@ classes:
   abnormal: PATO:0000460
   chemical entity: CHEBI:24431
   role: CHEBI:50906
+  anatomical entity: UBERON:0001062
 
 relations:
   inheres_in: RO:0000052
   has_modifier: RO:0002573
   has_part: BFO:0000051
   has_role: RO:0000087
+  part_of: BFO:0000050
 
 annotationProperties:
   exact_synonym: oio:hasExactSynonym
@@ -35,6 +37,6 @@ def:
   - role
 
 equivalentTo:
-  text: "'has_part' some ('amount' and ('inheres_in' some ('chemical entity' and ('has_role' some %s))) and ('has_modifier' some 'abnormal'))"
+  text: "'has_part' some ('amount' and ('inheres_in' some ('chemical entity' and ('has_role' some %s) and ('part_of' some 'anatomical entity'))) and ('has_modifier' some 'abnormal'))"
   vars:
   - role