diff --git a/setup.py b/setup.py
index 6aba2de79..2a8e8eefc 100755
--- a/setup.py
+++ b/setup.py
@@ -244,25 +244,29 @@ def append_nvcc_threads(nvcc_extra_args):
             ),
         }
 
-    ext_modules.append(
-        CUDAExtension(
-            name="selective_scan_cuda",
-            sources=[
-                "csrc/selective_scan/selective_scan.cpp",
-                "csrc/selective_scan/selective_scan_fwd_fp32.cu",
-                "csrc/selective_scan/selective_scan_fwd_fp16.cu",
-                "csrc/selective_scan/selective_scan_fwd_bf16.cu",
-                "csrc/selective_scan/selective_scan_bwd_fp32_real.cu",
-                "csrc/selective_scan/selective_scan_bwd_fp32_complex.cu",
-                "csrc/selective_scan/selective_scan_bwd_fp16_real.cu",
-                "csrc/selective_scan/selective_scan_bwd_fp16_complex.cu",
-                "csrc/selective_scan/selective_scan_bwd_bf16_real.cu",
-                "csrc/selective_scan/selective_scan_bwd_bf16_complex.cu",
-            ],
-            extra_compile_args=extra_compile_args,
-            include_dirs=[Path(this_dir) / "csrc" / "selective_scan"],
+    # selective_scan_cuda is a Mamba-1 CUDA extension that does not compile
+    # on ROCm/HIP.  Mamba-2 and Mamba-3 use Triton kernels instead, so this
+    # extension is not needed on HIP builds.
+    if not HIP_BUILD:
+        ext_modules.append(
+            CUDAExtension(
+                name="selective_scan_cuda",
+                sources=[
+                    "csrc/selective_scan/selective_scan.cpp",
+                    "csrc/selective_scan/selective_scan_fwd_fp32.cu",
+                    "csrc/selective_scan/selective_scan_fwd_fp16.cu",
+                    "csrc/selective_scan/selective_scan_fwd_bf16.cu",
+                    "csrc/selective_scan/selective_scan_bwd_fp32_real.cu",
+                    "csrc/selective_scan/selective_scan_bwd_fp32_complex.cu",
+                    "csrc/selective_scan/selective_scan_bwd_fp16_real.cu",
+                    "csrc/selective_scan/selective_scan_bwd_fp16_complex.cu",
+                    "csrc/selective_scan/selective_scan_bwd_bf16_real.cu",
+                    "csrc/selective_scan/selective_scan_bwd_bf16_complex.cu",
+                ],
+                extra_compile_args=extra_compile_args,
+                include_dirs=[Path(this_dir) / "csrc" / "selective_scan"],
+            )
         )
-    )
 
 
 def get_package_version():